Authors: Hidenobu Hashimoto Yoshimitsu Fukushima Shinichiro Kumita Masaaki Miyamoto Gen Takagi Junichi Yamazaki Takanori Ikeda
Publish Date: 2016/11/21
Volume: 35, Issue: 2, Pages: 68-77
Abstract
The purpose of this study was to estimate the severity of the participants’ lower limb ischemia by calculating the lower limb muscletobackground ratio LMBR using lower limb perfusion singlephoton emission computed tomographycomputed tomography SPECT/CT and to evaluate the prognostic value of LMBR in peripheral artery disease PAD patientsThis retrospective study consists of 38 patients with PAD 70 ± 12 years and observed over 1 year who were included in the analysis All participants underwent lower limb perfusion SPECT/CT LMBR was calculated by dividing counts/volume in lower limb muscle by mean counts/volume of background All patients were divided into two groups based on their LMBR value and observed for the occurrence of a major adverse event MAEThe high and low LMBR groups consisted of 26 and 12 patients respectively The median LMBR in the high group was 959 611–1187 while that in the low group was 435 385–499 A significantly higher number of patients in the low LMBR group experienced MAE than in the high LMBR group 7 of 12 vs 1 of 26 p 0001Takanori Ikeda has received Grant support through his institution from Daiichi Sankyo BristolMyers Squibb and Boehringer Ingelheim and honoraria for lectures from Bayer Healthcare Daiichi Sankyo BristolMyers Squibb Pfizer TanabeMitsubishi and Ono Pharmaceutical Regarding this study all authors declare that there is no potential conflict of interest
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