Subperiosteal tissue expansion an experimental st

Authors: Ibrahim Askar Bizden Tavil Sabuncuoglu Mustafa Rıza Ozbek

Publish Date: 2003/09/11

Volume: 26, Issue: 6, Pages: 306-311

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Abstract

Periosteal flaps have been used to cover bone defects There are no sufficient data on whether expanded periosteum can be used to repair bone defects after subperiosteal tissue expansion In this experimental study 14 male dogs which were 2 yearsold and weighed 145–160 kg were used to investigate the repair of bony defects with expanded periosteum Rectangular tissue expanders measuring 50 mm in width 70 mm in length and 20 mm in height volume 20 ml were used The dogs were divided into two groups each of seven dogs one control group and one experimental group In each dog a pocket 50×70 mm in size was prepared in parietal area and a periosteal area 30×40 mm in size was marked out A rectangular tissue expander was inserted into the pocket In the control group the tissue expanders were not inflated On the seventh postoperative day the tissue expander inflation with normal saline 5 ml per 2 days was started in the experimental group After 15 days the previously marked out periosteal area was measured A specimen was taken from this periosteal tissue for histopathological evaluation A bone defect 20×20 mm in size was created beneath expanded periosteal tissue and this defect was covered with the expanded periosteal tissue After 15 days a histopathological evaluation was carried out Statistical analysis was carried out using the Mann–Whitney Utest The area of periosteum expanded was more in the experimental group than that of the control group p005 After removal of the tissue expander both in the control and subperiosteal tissue expansion group osteoblastic lining of the expanded periosteum increased vascularity and granulation tissue was noted Following 15 days woven and lamellated bone tissue was formed both in the control and subperiosteal expansion group In the subperiosteal expansion group there was greater bone formation the expanded periosteum was thickened and thickened lamellated bone was covered by active osteoblasts It is concluded that subperiosteal tissue expansion may be worthwhile to provide large periosteal flaps for the repair of large bone defects by increasing osteogenic capacity

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