Authors: Emilio Quaia Renato Toffanin Giuseppe Guglielmi Maja Ukmar Alexia Rossi Bruno Martinelli Maria Assunta Cova
Publish Date: 2008/04/11
Volume: 37, Issue: 6, Pages: 511-517
Abstract
After the imaging of a phantom consisting of two sealed 50ml test objects with different concentrations 30 and 90 weight/volume of copper sulphate the T2 mapping of patellar articular cartilage was performed in 35 patients 21 male and 14 female mean age ± SD 42 ± 17 years with moderate degree of patellar osteoarthritis Turbospinecho TSE TR milliseconds/minimum–maximum TE milliseconds 3000/15–120 total acquisition time 5 min 52 s and GRASE TR milliseconds/minimum–maximum TE milliseconds 3000/15–120 total acquisition time 1 min 51 s were employed In each patient patellar cartilage was segmented at nine locations three superior three central and three inferior by manually defined regions of interest T2 relaxation times were calculated using a linear fit applied to the logarithm of signal intensity decayIn the phantom the T2 values measured by GRASE were similar to those measured by MR spectroscopy test object 1 481 ms vs 51 ms test object 2 668 ms vs 71 ms P 005 Wilcoxon test In patients GRASE and TSEderived T2 values demonstrated good agreement mean difference ± SD 181 ± 363 ms The withinpatient coefficient of variation was 22 for TSE and 23 for GRASE
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