Management of highgrade dysplasia

Authors: Francesco Palazzo Piero M Fisichella Marco G Patti

Publish Date: 2008/10/11

Volume: 10, Issue: 3, Pages: 240-245

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Abstract

Highgrade dysplasia is the last stage before the development of adenocarcinoma Despite the fact that the lesion is not yet invasive it has tremendous potential to become malignant The approach to the disease has clinicians divided between immediate intervention with surgical resection or continued endoscopic surveillance proof of the unclear natural history Much knowledge has been acquired recently regarding application of surveillance and outcomes of esophageal resection Also many endoscopic techniques for treating highgrade dysplasia have been studied in depth Results on their safety efficacy and complication rates have recently become available This review analyzes the progress in the understanding and treatment of highgrade dysplasia during the past 24 to 36 months and examines how this new information plays a role in the disease’s treatment algorithm

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