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Title of Journal: Curr Gastroenterol Rep

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Abbravation: Current Gastroenterology Reports

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Current Science Inc.

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10.1007/978-1-4471-0165-9

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1534-312X

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Intraepithelial Lymphocytes To Serve and Protect

Authors: Brian S Sheridan Leo Lefrançois
Publish Date: 2010/10/02
Volume: 12, Issue: 6, Pages: 513-521
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Abstract

The mucosal immune system is constantly exposed to a wide range of commensal and potentially pathogenic microbial species Chronic exposure to foreign organisms makes generation of an appropriate immune response critical in maintaining a balance between elimination of harmful pathogens peaceful coexistence with commensals and prevention of autoimmunity Intestinal intraepithelial lymphocytes provide a first line of defense at this extensive barrier with the outside world and as such understanding their role in immunity is critical


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