Journal Title
Title of Journal: Biochem Genet
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Abbravation: Biochemical Genetics
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Authors: JingFen Kang XiangLong Li RongYan Zhou LanHui Li FuJun Feng XiuLi Guo
Publish Date: 2009/10/24
Volume: 47, Issue: 11-12, Pages: 911-
Abstract
Regarding the report in “Bioinformatics analysis of lactoferrin gene for several species” JF Kang XL Li RY Zhou LH Li FJ Feng and XL Guo Biochemical Genetics 46 Nos 5/6 June 2008 that Trp 8 is unique to cows undergraduate Memori Otsuka and Dr Justen Whittall of Santa Clara University have pointed out that Trp 8 is also found in the buffalo sequence The authors have examined the data and agree with Otsuka and Whittall that the shared presence of Trp 8 in cow and buffalo and likely several other closely related yet unsampled bovids suggests that buffalo also produces lactoferrin proteins with antimicrobial activityThe authors therefore suggest that the sentence “By analyzing 15 amino acid residues within and among species it was found that Trp 6 was conserved among all species except Camelus dromedarius Phe6 and Trp 8 existed only in Bos taurus which is why cow lactoferricin was more effective against microbes than the others” appearing on page 318 be changed to “By analyzing 15 amino acid residues within and among species it was found that Trp 6 was conserved among all species except Canis familiaris Phe6 and Trp 8 existed only in Bos taurus and Bubalus bubalis which is why cow lactoferricin was more effective against microbes than the others”
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