Authors: Abdul Mueed Bidchol A Wilfred P Abhijna R Harish
Publish Date: 2009/03/07
Volume: 4, Issue: 7, Pages: 1137-1143
Abstract
In this study antioxidant activities of aqueous and ethanolic extracts of Brassica oleracea L var italica were investigated The antioxidant properties of both extracts of Brassica oleracea L var italica were evaluated using different antioxidant tests including 1 1diphenyl2picrylhydrazyl DPPH radical scavenging superoxide radical scavenging inhibition of microsomal lipid peroxidation reduction of power and metal ion chelating activities Inhibition of superoxide scavenging by aqueous and ethanolic extracts showed an IC50 of 093 and 025 mg/ml respectively Metal ion chelation showed an IC50 of 035 mg/ml of both the extracts and was equipotent to positive control ethylenediamine tetraacetic acid The ethanolic extract of Brassica oleracea L var italica exhibited higher antioxidant activity in DPPH radical and superoxide anion scavenging than that of aqueous extract The results obtained in the in vitro models clearly suggest that Brassica oleracea L var italica is a natural source for antioxidants which could serve as a nutraceutical with potential applications in reducing the level of oxidative stress and related health benefits However comprehensive studies need to be conducted to ascertain the in vivo safety of such extracts in experimental animal models
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