Authors: Mohammad Javad Zare Sakhvidi AbdulRahman Bahrami Alireza Ghiasvand Hossein Mahjub Ludovic Tuduri
Publish Date: 2011/11/18
Volume: 184, Issue: 11, Pages: 6483-6490
Abstract
Occupational exposure to inhalational anesthetics occurs routinely in operating rooms It could induce serious health hazards and diseases This exposure assessment is a crucial step in determining risks In this study a penshaped holder for solidphase microextraction SPME sampler was successfully applied as a timeweighted average sampling tool for workshift exposure assessment of operation room staff to halothane It proved to be very convenient for use in occupational environments such as operation rooms Samples were analyzed by a gas chromatography–mass spectrometry The validity of the SPME method was checked in realworld conditions with Occupational Safety and Health Administration OSHA 103 standard method for the determination of inhalational anesthetics A good agreement between OSHA 103 and SPME methods was obtained and results demonstrated no statistically significant differences in anesthetic concentrations determined by the two analytical methods p ≥ 005 It is concluded that SPME in retracted mode could successfully be applied in occupational exposure assessment purposes
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