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Title of Journal: Exp Fluids

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Abbravation: Experiments in Fluids

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Springer-Verlag

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10.1007/s10853-016-9769-y

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1432-1114

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Imaging diffusion in a microfluidic device by thir

Authors: Uwe Petzold Andreas Büchel Steffen Hardt Thomas Halfmann
Publish Date: 2012/06/06
Volume: 53, Issue: 3, Pages: 777-782
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Abstract

We monitor and characterize nearsurface diffusion of miscible transparent liquids in a microfluidic device by third harmonic microscopy The technique enables observations even of transparent or indexmatched media without perturbation of the sample In particular we image concentrations of ethanol diffusing in water and estimate the diffusion coefficient from the third harmonic images We obtain a diffusion coefficient D = 460 ± 30 μm2/s which is consistent with theoretical predictions The investigations clearly demonstrate the potential of harmonic microscopy also under the challenging conditions of transparent fluids

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