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Title of Journal: Int Arch Occup Environ Health

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Abbravation: International Archives of Occupational and Environmental Health

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Springer Berlin Heidelberg

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DOI

10.1002/app.1972.070161217

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1432-1246

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Micronuclei in lymphocytes from radon spa personne

Authors: Friedo Zölzer Zdeněk Hon Zuzana Freitinger Skalická Renata Havránková Leoš Navrátil Jozef Rosina Jiří Škopek
Publish Date: 2012/07/07
Volume: 86, Issue: 6, Pages: 629-633
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Abstract

The frequency of micronucleuscontaining cells and the percentage of centromerefree micronuclei micronuclei containing only acentric fragments was determined in peripheral blood lymphocytes of 42 individuals working at the Jáchymov spa and 42 control individualsThere was a highly significant increase in the frequency of micronucleuscontaining cells as well as the percentage of centromerefree micronuclei in the lymphocytes of spa personnel versus controls No individual dosimetry data were available A comparison with results from currently active uranium miners suggests that the individuals examined at the Jáchymov spa had accumulated effective doses in the order of several tens of mSv very similar to those of the minersWe thank Ing Hana Placakova for reliable technical assistance and Ing Ladislav Beránek CSc MBA for help with the statistics These investigations have been supported by the Czech Ministry of Education Youth and Sports within the framework of the National Research Program II NPV II project 2B08001

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