Authors: Jairam Vanamala Andrew C Kester Adam L Heuberger Lavanya Reddivari
Publish Date: 2012/04/04
Volume: 67, Issue: 2, Pages: 111-119
Abstract
Obesity is closely associated with increased incidence of cardiovascular diseases cancer insulin resistance and immune dysfunction and thus obesitymitigation strategies should take into account these secondary pathologies in addition to promoting weight loss Recent studies indicate that black cumin Nigella sativa has cardioprotective anticancer antidiabetic antioxidant and immunemodulatory properties While black cumin and/or its major bioactive constituent thymoquinone have demonstrated bioactivity in a variety of disease models the mechanisms of action are largely unknown Given the growing interest in and the use of functional foods and nutraceuticals as well as the increase in obesity and chronic diseases worldwide further research into the therapeutic/preventive effects of black cumin may be beneficial
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