Authors: Alexandrios Briasoulis George L Bakris
Publish Date: 2013/01/22
Volume: 15, Issue: 3, Pages: 340-
Abstract
Chronic kidney disease CKD is associated with accelerated cardiovascular disease CVD risk and a higher CVD event rate Substantial data from prospective cohort studies support the concept that dialysis patients as well as those with advanced stage stages 3–5 CKD are associated with an increased risk for allcause and cardiovascular mortality The risk for coronary artery disease CAD increases exponentially with declining kidney function ie stage 3 or higher CKD Indeed CVD accounts for more than 50 of deaths in patients with CKD CKD patients are more likely to die of CVD than to progress to end stage kidney disease This increase in CV risk is commonly attributed to coexistence of numerous traditional and nontraditional risk factors for the development of CVD that frequently accompany reduced kidney function Therefore CKD itself is now considered an independent CVD risk factor and a coronary artery disease CAD equivalent for allcause mortality All patients at risk for CAD should be evaluated for kidney disease Treatments used for management of established CAD might have similar benefits for patients with concomitant CKD
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