Authors: Daniel Lindholm Stefan James
Publish Date: 2016/06/16
Volume: 18, Issue: 8, Pages: 74-
Abstract
The evolution of percutaneous coronary intervention has been considerable Coronary stents were introduced to avoid vessel recoil and reduce acute and late vessel complications Later drugeluting stents were developed to decrease the neointimal hyperplasia associated with bare metal stents in order to reduce restenosis However very late stent thrombosis remains problematic and the permanent presence of a metal stent could be associated with local inflammation and impaired vascular physiology Thus bioresorbable stents have been developed to prevent recoil initially when this risk is the highest with subsequent degradation over time to avoid longterm complications of the presence of stents in the coronary vasculature Here we review the current status of bioresorbable stents in percutaneous coronary intervention PCI with focus on the platforms that have been studied the most ABSORB DESolve and DREAMS In terms of clinical outcomes bioresorbable stents have not yet shown superiority compared with current generation drugeluting stents but rather a signal of increased stent thrombosis Further development and longerterm studies are needed before the routine implementation of bioresorbable stents in clinical practice
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