Authors: S Vincent A Daiwile S S Devi M J Kramer M F Besser B S Murty Jatin Bhatt
Publish Date: 2014/09/26
Volume: 46, Issue: 6, Pages: 2422-2430
Abstract
Metallic glasses are a potential and compatible implant candidate for biomedical applications In the present investigation a comparative study between novel Zr55Co30Ti15 and Cu60Zr20Ti20 metallic glasses is carried out to evaluate in vitro biocompatibility using simulated body fluids The biocorrosion behavior of Zr and Cubased metallic glasses in different types of artificial body fluids such as artificial saliva solution phosphatebuffered saline solution artificial blood plasma solution and Hank’s balanced saline solution is evaluated using potentiodynamic polarization studies at a constant body temperature of 31015 K 37 °C Surface morphology of samples after biocorrosion experiments was observed by scanning electron microscopy In vitro cytotoxicity test on glassy alloys were performed using human osteosarcoma cell line as per 109935 guidelines from International Organization for Standardization The comparative study between Zr and Cubased glassy alloys provides vital information about the effect of elemental composition on biocompatibility of metallic glassesOne of the authors Jatin Bhatt is thankful to INDO US Science and Technology forum for Fellowship award IUSSTF Fellowship/162012 to carry out part of above research work at the Ames Laboratory USDOE Iowa State University This work was supported by the US Department of Energy DOE Office of Basic Energy Science Division of Materials Science and Engineering The research was performed at the Ames Laboratory which is operated for the US DOE by Iowa State University under contract DEAC0207CH11358 The authors’ are also thankful to Technical Education Quality Improvement Program TEQIP II Government of India for providing financial assistance
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