Authors: Gustavo Davi Rabelo José Narciso Rosa Assunção Pascale Chavassieux Haroldo Arid Soares Fabio Abreu Alves Celso Augusto Lemos
Publish Date: 2014/10/15
Volume: 14, Issue: 3, Pages: 699-705
Abstract
Bisphosphonate BP therapy in the treatment of bone diseases and malignancy may induce a major side effect known as bisphosphonaterelated osteonecrosis of the jaws BRONJ A particular view of this condition is reported in this case series investigating eight patients The aim of the study was to evaluate the BRONJ lesions concerning their aspects and progression Also identify if it is possible to predict the degree of severity in these casesThe patients presented with specific peculiarities and the BRONJ lesions varied in several characteristics The BRONJ lesions ranged from simple to severe conditions and the complicated cases presented with major pain swelling secondary infection and an extensive necrotic area classified with high grade of severityThe patients presented here confirm the existence of a relation between multiple features and BRONJ and to understand the whole process of aggravation all systemic and local information have to be taken into account together with all data related to the BP utilized Regardless of the low incidence of this side effect in relation to osteoporosis treatment in some cases the BRONJ may become a severe condition and compromise the patient’s quality of life
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