Noninjected illicit drug use and infectious disea

Authors: Mark D Barton Amir Qureshi Anita Vijapura H Thomas Temple

Publish Date: 2015/05/26

Volume: 16, Issue: 4, Pages: 623-629

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Abstract

This study assessed the relationship of noninjected illicit drug use and infectious disease seropositivity for human immunodeficiency virus HIV1 hepatitis B virus HBV hepatitis C virus HCV and Syphilis In a retrospective review of 986 donor charts recovered from 2009 to 2011 at a single tissue bank the absence of reported noninjected illicit drug use corresponded with seropositivity in 661  of recovered donors while reported illicit drug use in the medical and social history corresponded with seropositivity in 1125  representing a 70  increased risk There was no significant difference noted for overall seropositivity rates between types on noninjected illicit drugs although donors that used cocaine had a higher incidence of HIV while marijuana use was associated with a higher rate of HBV HCV and syphilis positivity Toxicology screening results were not an accurate predictor of seropositivity PPV = 377  NPV = 9156  Further the degree of relationship between the donor and the next of kin had no bearing on the veracity of actual drug use when comparing the response of the medicalsocial history and the toxicology screen

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