Authors: Zuzana Obertová Ross Lawrenson Nina Scott Michael Holmes Charis Brown Chunhuan Lao Leanne Tyrie Peter Gilling
Publish Date: 2015/01/06
Volume: 20, Issue: 4, Pages: 814-820
Abstract
All Māori men 150 diagnosed with prostate cancer in the Midland Cancer Network region between 2007 and 2010 were identified from the NZ Cancer Registry and frequency agematched with three randomly sampled NZ European men Clinical records of these men were searched for information on clinical stage at diagnosis comorbidities and type of treatment for localised diseaseThe final cohort included 136 Māori and 400 NZ European men of whom 97 Māori and 311 NZ European were diagnosed with localised prostate cancer Māori men were twice as likely to be diagnosed with distant metastases compared with NZ European men 191 vs 98 Māori men with localised disease were less likely to be treated with radical prostatectomy compared with NZ European men RR 066 95 CI 048 090 Multivariate regression analysis adjusted for age D’Amico risk strata comorbidities and socioeconomic deprivation showed that Māori men were more likely to be managed expectantly RR 174 95 CI 106 257Differences between Māori and NZ European men observed in the management of localised prostate cancer cannot be readily explained by patient characteristics such as comorbidities or risk assessment at diagnosis Poorer outcomes for Māori men may not only be related to later stage at diagnosis but differences in treatment modalities may also be a factorThis study was supported by Health Research Council of New Zealand HRC Partnership Programme grant number 11/082 entitled ‘The costs and complications of screening for prostate cancer’ We are very grateful to all contributing specialists their departments and practices and to the regional community laboratory Pathlab
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