Authors: Bart Wessels Jolita Ciapaite Klaas Nicolay Jeanine Prompers
Publish Date: 2015/03/17
Volume: 9, Issue: 3, Pages: 109-110
Abstract
Pioglitazone is a PPAR agonist that redirects lipids from ectopic sites into subcutaneous adipose tissue and is hypothesized to improve mitochondrial function in skeletal muscle This study assessed whether the insulinsensitizing effect of pioglitazone is accompanied by improved skeletal muscle mitochondrial function and intramyocellular lipid IMCL levels in Zucker diabetic fatty rats using 31P and 1H magnetic resonance spectroscopy MRS
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