Journal Title
Title of Journal: Lung
|
|
|
|
|
|
|
|
|
|
Authors: Luis CorralGudino Alberto GarcíaZamalloa Cristina PradaGonzález Silvia Bielsa Duckens Alexis Jorge TaboadaGómez Pilar R DosSantosGallego María A AlonsoFernández Jose M Porcel
Publish Date: 2016/07/11
Volume: 194, Issue: 5, Pages: 847-854
Abstract
The frequency of “complicated” pleural effusions CPE ie pleural fluid pH ≤ 72 and/or glucose ≤60 mg/dL of tuberculous origin CTPE is not well reported This study aims to quantify their prevalence and develop a score to differentiate CTPE from complicated parapneumonic effusions CPPERetrospective analysis of databases from three Spanish hospitals which included patients with CTPE and CPPE Forty percent of the study population served to generate a scoring system COMPLES COMplicated PLeural Effusion Score that was further validated in the remaining 60 During the study period 1992–2015 549 patients were diagnosed with tuberculous effusions and 434 parapneumonic effusions of whom 25 and 64 respectively had CPE COMPLES was based on the combination of pleural fluid adenosine deaminase ADA the percentage of mononuclear cells MNC pH and age The cutoff values and assigned scores were ADA 46 IU/L 0 points 46–100 IU/L 4 points ≥100 IU/L 6 points MNC 10 0 points 10–50 3 points 50 8 points pH 707 0 points 707–720 3 points 720 5 points and age ≥30 0 points 30 years 3 points A sum of 12 or more points had 97 sensitivity 92 specificity likelihood ratio positive 123 likelihood ratio negative 003 and area under the curve of 0947 for identifying CTPE versus CPPE in the validation set
Keywords:
.
|
Other Papers In This Journal:
|