Authors: Rocío OlmedoRequena Carmen AmezcuaPrieto Juan de Dios LunaDelCastillo AnneMary LewisMikhael Juan MozasMoreno Aurora BuenoCavanillas José Juan JiménezMoleón
Publish Date: 2016/03/12
Volume: 20, Issue: 6, Pages: 1296-1304
Abstract
Background Inadequate maternal nutrition is regarded as one of the most important indicators of fetal growth The aim of this study was to analyze the associated risk of having a small for gestational age SGA infant according to the mother’s dairy intake during the first half of pregnancy Methods A prospective cohort study was performed using 1175 healthy pregnant women selected from the catchment area of Virgen de las Nieves University Hospital Granada Spain SGA was defined as neonates weighing less than the 10th percentile adjusted for gestational age Factors associated with SGA were analyzed using logistic regression models Population attributable fractions of SGA according to dairy intake were estimated Results Dairy intake among women who gave birth to SGA infants was 5139 versus 5903 g/day for women with appropriate size for gestational age infants P = 0003 An increased intake of dairy products by 100 g/day during the first half of pregnancy decreased the risk of having a SGA infant by 110 aOR = 089 083 096 A dose–response gradient between dairy intake and SGA was observed Conclusions An inadequate intake of dairy products is associated with a higher risk of SGA Our results suggest a possible causal relation between dairy intake during pregnancy and the weight of the newborn although we cannot discard residual confounding These results should be further supported by properly designed studiesThe authors thank Jean Sanders for improving the use of English in the manuscript The results of this study are part of PhD work of Rocío OlmedoRequena The present study was funded by FIS Scientific Research Project PI 03/1207 and Junta de Andalucía Excellence Project 2005 CTS 942 as well as the Biomedical Research Centre Network for Epidemiology and Public Health CIBERESP
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