Inhibitory Effects of Mediterranean Sponge Extract

Authors: Claire Hellio Maria Tsoukatou JeanPhilippe Maréchal Nick Aldred Claude Beaupoil Anthony S Clare Constantinos Vagias Vassilios Roussis

Publish Date: 2005/06/30

Volume: 7, Issue: 4, Pages: 297-305

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Abstract

One of the most promising alternative technologies to antifouling paints based on heavy metals is the development of coatings whose active ingredients are compounds naturally occurring in marine organisms This approach is based on the problem of epibiosis faced by all marine organisms and the fact that a great number of them cope with it successfully The present study investigated the antifouling activity of a series of extracts and secondary metabolites from the epibiontfree Mediterranean sponges Ircinia oros I spinosula Cacospongia scalaris Dysidea sp and Hippospongia communis Antifouling efficacy was evaluated by the settlement inhibition of laboratoryreared Balanus amphitrite Darwin cyprids The most promising activity was exhibited by the metabolites 224acetoxyoctaprenyl14hydroquinone 8a dihydrofurospongin II 10 and the alcoholic extract of Dysidea spWe thank the National Fellowship Foundation for provision of a fellowship to one of us MT and the General Secretariat for Research and Technology and the University of Athens for financial support of the Greek research team The British team was supported by an award from the US Office of Naval Research N000140210311 We also thank Dr Dan Rittschof Dr Nikos Mihopoulos Mr Dennis Abatis Mr Lefteris Marinos and Mrs Sheelagh Henry for their assistance on different aspects of the present investigation

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