Authors: Paweł Petkow Dimitrow Piotr Klimeczek Rozemarijn Vliegenthart Mieczysław Pasowicz Matthijs Oudkerk Piotr Podolec Wiesława Tracz Jacek S Dubiel
Publish Date: 2007/07/10
Volume: 24, Issue: 1, Pages: 77-83
Abstract
In HCM patients NSVT in Holter monitoring is a risk factor for sudden cardiac death however its positive predictive value is low Varying risk of sudden death related to NSVT may be dependent on the heterogeneous extent of the arrhythmogenic substrate which seems to be visible as hyperenhancement in gadoliniumenhanced magnetic resonance imaging MRIIn HCM patients with NSVT 97 had some extent of hyperenhancement on MRI ranging from 1 to 76 g The mean mass of hyperenhanced myocardium was 19 ± 18 g 81 ± 76 of total left ventricular mass In HCM patients without NSVT a significantly lower percentage of patients 60 had hyperenhancement P 005 However the amount of hyperenhanced myocardium was not significantly different 13 ± 19 g 63 ± 91 of total left ventricular mass P 005Hyperenhancement was visible in almost all HCM patients with NSVT 97 and in a significantly lower percentage of patients without NSVT 60 Whether this finding explains the increased risk of sudden death in case of NSVT is not clear since the extent of hyperenhancement was not significantly different between the two groups
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