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Title of Journal: Int J Cardiovasc Imaging

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Abbravation: The International Journal of Cardiovascular Imaging

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Springer Netherlands

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DOI

10.1007/s13277-015-3501-4

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1573-0743

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Quantitative plaque characterization with coronary

Authors: Paul Schoenhagen Mitya Barreto Sandra S Halliburton
Publish Date: 2007/11/27
Volume: 24, Issue: 3, Pages: 313-316
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Abstract

In the current issue of the journal Knollmann et al describe results from a quantitative postmortem coronary plaque analysis with CT angiography CTA in comparison to histology 1 Plaque burden was quantified on a persegment and a perpatient basis and demonstrated an overall fair correlation to histology but significant overestimation with CT Further analysis of calcified and noncalcified plaque components demonstrated best correlation for calcified plaque with overestimation of plaque burden In contrast there was relatively poor correlation for noncalcified plaque components and in particular the lipid core area which was underestimated with CT in comparison to histology Importantly the correlation was better for patientbased analysis average of all segments versus segmentbased analysis For segmentbased analysis of individual plaques the correlation between histology and CT was limited for small plaques

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