Authors: C Pérez M Dolande M Moya A Roselló Claudia R Hartung de Capriles M E Landaeta S MataEssayag
Publish Date: 2008/05/30
Volume: 166, Issue: 3, Pages: 149-153
Abstract
Cryptococcus neoformans is one of the medically important yeastlike fungi C neoformans var gatti has been made a species C gatti In our country there are few studies about these two species and their serotypes The aim of this study was to determine the distribution of C neoformans and C gattii and their serotypes in Venezuelan clinical isolates One hundred and twenty C neoformans and 12 C gattii clinical isolates were identified by lcanavanine glycine and bromothymol blue agar media CGB These were investigated by agglutination and adsorption studies with anticryptococcal sera which were produced by rabbit immunization Of the 132 isolates 598 were typed serotype A C neoformans followed by 258 serotype D C neoformans 53 serotype AD C neoformans and 53 were typed serotype C var gattii Additionally 38 were serotype B C gattiiWe thank Mireya Mendoza Departamento de Micologia Instituto de Biomedicina Caracas for the donation of the control strains and Mercedes Panizo Departamento de Micología Instituto Nacional de Higiene Caracas for donation of the serotype B control strain originally from Belgium This work was partly supported by the project CDCH Nº PI 090053842004 and Fonacit Project Nº LAB2000001587 of the “Rafael Rangel” culture collection
Keywords: