Hydrophobicity effect on interactions between orga

Authors: S L Yefimova G Ya Gural’chuk A V Sorokin Yu V Malyukin I A Borovoy A S Lubyanaya

Publish Date: 2008/12/10

Volume: 75, Issue: 5, Pages: 658-663

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Abstract

Interactions between the cationic polymethine dyes 33′diethyloxacarbocyanaine iodide DiOC2 33′dioctadecyloxacarbocyanine iodide DiOC18 and 11′dioctadecyl333′3′tetramethylindocarbocyanine perchlorate DiI in the nanoscale volume of anionic sodium dodecylsulfate SDS micelles have been studied using optical spectroscopy techniques The solubilization of pairs of dye molecules DiOC18/DiI or DiOC2/DiI within SDS micelles was monitored by Forster resonance energy transfer FRET between the dyes in each pair The influence of the hydrophobicity of the dyes DiOC2 and DiOC18 on the efficiency of their binding to SDS micelles and consequently on the efficiency of FRET between DiOC18 and DiI or DiOC2 and DiI fluorophors has been analyzed It has been shown that hydrophobic interactions in addition to electrostatic interactions are of key importance for the binding between the positively charged dyes and negatively charged surfactant micelles

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