Authors: Shalini Kushwaha Paramjit Chawla Anita Kochhar
Publish Date: 2012/10/05
Volume: 51, Issue: 11, Pages: 3464-3469
Abstract
Menopause is a gradual threestage process that concludes with the end of periods and reproductive life The antioxidant enzyme system get affected in postmenopause due to deficiency of estrogen which has got antioxidant properties The objective of the present study was therefore to analyze the effect of supplementation of drumstick and amaranth leaves powder on blood levels of antioxidant and marker of oxidative stress Ninety postmenopausal women aged 45–60 years were selected and divided into three groups viz Group I II and III having thirty subjects in each group The subjects of group II and III were supplemented daily with 7 g drumstick leaves powder DLP and 9 g amaranth leaves powder ALP respectively for a period of 3 months in their diet The subjects of group I was not given supplementation Serum retinol serum ascorbic acid glutathione peroxidase superoxide dismutase and malondialdehyde were analyzed before and after supplementation Fasting blood glucose and haemoglobin level of the subjects were also analyzed The data revealed that supplementation of DLP and ALP significantly increased serum retinol 88 and 50 serum ascorbic acid 444 and 59 glutathione peroxidase 180 and 119 superoxide dismutase 104 and 108 whereas decrease in marker of oxidative stress ie malondialdehyde 163 and 96 in postmenopausal women of group II and group III respectively A significant p ≤ 001 decrease was also observed in fasting blood glucose level 135 and 104 and increase in haemoglobin 175 and 53 in group II and group III respectively The results indicated that these plants possess antioxidant property and have therapeutic potential for the prevention of complications during postmenopause
Keywords: