Authors: Kimihide Kusafuka Tetsuro Onitsuka Tomoko Miki Chika Murai Toshihito Suda Tomohito Fuke Tomoyuki Kamijo Yoshiyuki Iida Takashi Nakajima
Publish Date: 2013/12/27
Volume: 47, Issue: 4, Pages: 240-245
Abstract
Squamous cell carcinoma SCC with rhabdoid features SCCRF is extremely rare in the oral cavity We report herein a case of oral SCCRF The patient was a 69yearold Japanese woman who had been suffering from a mass in the right lower gingiva Right hemimandibulectomy was performed The gingival tumor was composed of pleomorphic noncohesive ovoid tumor cells with abundant cytoplasm and eccentric nuclei which were positive for both pancytokeratin and vimentin In another portion moderately differentiated SCC and carcinoma in situ were also seen A transition zone existed between the components Finally we diagnosed SCCRF Four months after the operation multiple bone metastases lung and skin metastases and marked hypercalcemia were found SCCRF therefore might be more aggressive than the usual type of oral SCCThe author thanks Mr Isamu Hayashi Mr Yoichi Watanabe Ms Sachiyo Oono Ms Kaori Nagata Mr Hiroshi Tashiro Mr Koji Muramatsu Mr Masatake Honda Mr Masato Abe Ms Chiho Tashiro Mr Takuya Kawasaki Mr Shogo Fujii and Ms Kazumi Yamamoto the staff of the Pathology Division Shizuoka Cancer Center Shizuoka Japan for excellent technical assistance He is also grateful to Mr Daniel Mrozek Medical English Service Kyoto Japan for his valuable help with the English editing of this manuscript
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