Authors: S GruberBlum N Riepl J Brand C Keibl H Redl R H Fortelny A H PetterPuchner
Publish Date: 2014/05/06
Volume: 18, Issue: 5, Pages: 761-769
Abstract
Atraumatic fixation is a key element of modern hernia repair Two different concepts of selfadhering meshes were directly compared in this study Adhesix® AH is coated with polyethylene glycol PEG and polyvinylpyrrolidone PVP whereas Parietene Progrip® PP relies on the mechanical principle of micro grips made of polylactic acid PLA These meshes are the main competitors in the fieldAH and PP were tested in Sprague–Dawley rats at 14 and 90 days Four groups were operated n = 8 animals per group Two meshes were implanted per animal in an operation model of onlay hernia repair Dislocation tissue integration and foreignbody reaction were evaluatedAH dislocated significantly more frequently every second mesh at both time points of observation than PP Tissue integration was good with PP and could not be reliably assessed in AH due to frequent dislocation Histologic examination revealed only a mild foreign body reaction in all groups
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