Journal Title
Title of Journal: J of Cardiovasc Trans Res
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Abbravation: Journal of Cardiovascular Translational Research
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Authors: William E Kraus Christopher B Granger Michael H Sketch Mark P Donahue Geoffrey S Ginsburg Elizabeth R Hauser Carol Haynes L Kristin Newby Melissa Hurdle Z Elaine Dowdy Svati H Shah
Publish Date: 2015/08/14
Volume: 8, Issue: 8, Pages: 449-457
Abstract
The CATHeterization GENetics CATHGEN biorepository was assembled in four phases First project startup began in 2000 Second between 2001 and 2010 we collected clinical data and biological samples from 9334 individuals undergoing cardiac catheterization Samples were matched at the individual level to clinical data collected at the time of catheterization and stored in the Duke Databank for Cardiovascular Diseases DDCD Clinical data included the following subject demographics birth date race gender etc cardiometabolic history including symptoms coronary anatomy and cardiac function at catheterization and fasting chemistry data Third as part of the DDCD regular followup protocol yearly evaluations included interim information vital status verified via National Death Index search and supplemented by Social Security Death Index search myocardial infarction MI stroke rehospitalization coronary revascularization procedures medication use and lifestyle habits including smoking Fourth samples were used to generate molecular data CATHGEN offers the opportunity to discover biomarkers and explore mechanisms of cardiovascular disease
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