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Title of Journal: J of Cardiovasc Trans Res

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Abbravation: Journal of Cardiovascular Translational Research

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Springer US

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DOI

10.1016/0020-7519(80)90049-1

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ISSN

1937-5395

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Improvement in Cardiovascular Risk Prediction with

Authors: Mindy M Pike Paul A Decker Nicholas B Larson Jennifer L St Sauver Paul Y Takahashi Véronique L Roger Walter A Rocca Virginia M Miller Janet E Olson Jyotishman Pathak Suzette J Bielinski
Publish Date: 2016/03/09
Volume: 9, Issue: 3, Pages: 214-222
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Abstract

The aim of this study was to compare the QRISKII an electronic health databased risk score to the Framingham Risk Score FRS and atherosclerotic cardiovascular disease ASCVD score Risk estimates were calculated for a cohort of 8783 patients and the patients were followed up from November 29 2012 through June 1 2015 for a cardiovascular disease CVD event During followup 246 men and 247 women had a CVD event Cohen’s kappa statistic for the comparison of the QRISKII and FRS was 022 for men and 023 for women with the QRISKII classifying more patients in the higherrisk groups The QRISKII and ASCVD were more similar with kappa statistics of 049 for men and 051 for women The QRISKII shows increased discrimination with area under the curve AUC statistics of 065 and 071 respectively compared to the FRS 059 and 066 and ASCVD 063 and 069 These results demonstrate that incorporating additional data from the electronic health record EHR may improve CVD risk stratification

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  1. Molecular Cardiology in Translation: Gene, Cell and Chemical-Based Experimental Therapeutics for the Failing Heart
  2. A Review of Human Pluripotent Stem Cell-Derived Cardiomyocytes for High-Throughput Drug Discovery, Cardiotoxicity Screening, and Publication Standards
  3. Models of Ventricular Structure and Function Reviewed for Clinical Cardiologists
  4. Bone-Marrow-Derived Side Population Cells for Myocardial Regeneration
  5. Short-Term Adjuvant Therapy with Terminalia arjuna Attenuates Ongoing Inflammation and Immune Imbalance in Patients with Stable Coronary Artery Disease: In Vitro and In Vivo Evidence
  6. Emerging MRI Methods in Translational Cardiovascular Research
  7. Letter from the Editors
  8. Determinants of Delayed Preconditioning Against Myocardial Stunning in Chronically Instrumented Pigs
  9. Stem Cell Therapy Trials: A Call for Standardization
  10. A Guide for a Cardiovascular Genomics Biorepository: the CATHGEN Experience
  11. Distinguishing Hypertrophic Cardiomyopathy-Associated Mutations from Background Genetic Noise
  12. Progenitor Cells Confer Plasticity to Cardiac Valve Endothelium
  13. Review of Stem Cell-Based Therapy for the Treatment of Cardiovascular Disease
  14. Right Ventricular Failure—A Continuing Problem in Patients with Left Ventricular Assist Device Support
  15. Clinical, Laboratory, and Pacing Predictors of CRT Response
  16. Deep Phenotyping of Systemic Arterial Hemodynamics in HFpEF (Part 1): Physiologic and Technical Considerations
  17. Renal Denervation: A Novel Non-pharmacological Approach in Heart Failure
  18. Oxidative Stress, Nox Isoforms and Complications of Diabetes—Potential Targets for Novel Therapies
  19. Why Is Infarct Expansion Such an Elusive Therapeutic Target?
  20. ST2-Based Precision Medicine in Device Management: the Next Frontier Beyond MADIT-CRT?
  21. Letter from the Editors
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