Journal Title
Title of Journal: J IRAN CHEM SOC
|
Abbravation: Journal of the Iranian Chemical Society
|
Publisher
Springer Berlin Heidelberg
|
|
|
|
|
|
Authors: Sina Bahrpeyma Bahram Hemmateenejad Katayoun Javidnia
Publish Date: 2015/09/29
Volume: 13, Issue: 2, Pages: 221-229
Abstract
DTIC or dacarbazine is a photosensitive drug which is analyzed by chromatography methods In this study chemometric methods were applied to resolve the UV–Vis absorbance spectra recorded during irradiation of DTIC by an artificial lighting source The photodegradation reaction was monitored at different pH media between 2 and 12 Multivariate curve resolutionalternative least square was then employed to simultaneously analyze the absorbance data matrices obtained at various pH media Factor analysis revealed the presence of five chemical species coexisting in the reaction media Regarding the analysis of concentration profiles of the detected species at different pH values three species were attributed to the different acid–base states of DTIC while the remaining components were considered as acid–base states of the photoproduct Eventually the presence of major photoproduct 2azahypoxanthine was confirmed by the HPLC method
Keywords:
.
|
Other Papers In This Journal:
- Facile and efficient preparation of nitriles through FeCl 4 –IL–SiO 2 -catalyzed direct oxidation of alcohols with hydrogen peroxide
- Adsorption behavior of cadmium ion onto synthetic ferrihydrite: effects of pH and natural seawater ligands
- Synthesis, characterization, lipoxygenase inhibitory activity and in silico molecular docking of biaryl bis(benzenesulfonamide) and indol-3-yl-hydrazide derivatives
- Fluoroferrate templated with HAmTAZ: X-ray single crystal, thermal behaviour, vibrational study and magnetic characterization
- Carbon dots: synthetic methods and applications as fluorescent probes for the detection of metal ions, inorganic anions and organic molecules
- Synthesis and characterization of chitosan coating of NiFe 2 O 4 nanoparticles for biomedical applications
- DFT study of CH 4 adsorption on the (5,0), (4,4), (5,5) and (6,6) single-walled carbon nanotubes. Calculated binding energies, NMR and NQR parameters
- Ionic liquid functionalized cellulose as an efficient heterogeneous catalyst for the facile and green synthesis of benzoxazine, pyrazine and quinoxaline derivatives in aqueous media
- A proton transfer and a nickel(II) compound including pyridine-2,6-dicarboxylate and Phenylhydrazinium ions: Synthesis, characterization, crystal structure and solution study
- Pharmacophore interactions analysis and prediction of inhibitory activity of 1,7-diazacarbazoles as checkpoint kinase 1 inhibitors: application of molecular docking, 3D-QSAR and RBF neural network
- Using thiourea ligand of gold-thiourea complex to facile direct synthesis of silica@gold core–shell nanostructures
- Synthesis and characterization of RuO 2 @ZrO 2 core–shell nano particles as heterogeneous catalyst for oxidation of benzylic alcohols in different conditions
- Adsorption of Pb(II) on a composite material prepared from polystyrene-alumina and activated carbon: Kinetic and thermodynamic studies
- Nuclear magnetic resonance study of the stoichiometry and stability of several HgX 2 –acetylemethylentriparatolylphosphorane complexes in various acetone–dimethylformamide mixtures
- A mild and clean Baeyer–Villiger oxidation of ketones using sodium peroxydisulfate as oxidant catalyzed by silica-supported aluminum chloride
- Dissolved carbon dioxide flotation-assisted in-syringe dispersive liquid–liquid microextraction coupled with microsampling flame atomic absorption spectrometry for selective determination of palladium in water samples
- Facile and efficient synthesis of pyrimido[1,2- a ]benzimidazole and tetrahydrobenzimidazo[2,1- b ]quinazolin-1(2 H )-one derivatives using Brönsted acidic ionic liquid supported on rice husk ash (RHA-[pmim]HSO 4 )
- Photodegradation of 2-nitrophenol catalyzed by CoO, CoS and CoO/CoS nanoparticles
- Forty years of research on osmolyte-induced protein folding and stability
- Characterization of galena surfaces and potassium isoamyl xanthate (KIAX) synthesized adsorption
- Doping of copper (I) oxide onto a solid support as a recyclable catalyst for acetylation of amines/alcohols/phenols and synthesis of trisubstituted imidazole
- A brief review of structural concepts of novel supramolecular proton transfer compounds and their metal complexes (part II)
- Facile and simple synthesis of pyrimido[4,5- d ]pyrimidinones and pyrano[2,3- d ]pyrimidinones catalyzed by nano-sized NS-C 4 (DABCO-SO 3 H) 2 ·4Cl
- The first report on the synthesis of new hantzsch N -Ethyldimetyl Acetal-1,4-dihydropyridines with aldehyde synthon under microwave irradiation
- An in silico approach to design peptide mimetics based on docking and molecular dynamics simulation of EGFR–matuzumab complex
- Aqua-mediated one-pot synthesis of Biginelli dihydropyrimidinone/thiones (DHPMs), Hantzsch dihydropyridines (DHPs), and polysubstituted pyridines sonocatalyzed by metal-supported nanocatalysts
- Application of SBA-Pr-NH 2 in one-pot three-component reaction of methylene-carbonyl compounds, acenaphthenequinone, malononitriles and exploration of its antimicrobial activity
- Hollow fiber solid phase microextraction coupled to square wave anodic stripping voltammetry for selective preconcentration and determination of trace levels of mercury in liquid fuel samples
|