Predictive utility of the NEOFFI for later substa

Authors: Caroline Parchetka Nicole Strache Bianca Raffaelli Isabel Gemmeke Katharina Weiß Eric Artiges Tobias Banaschewski Arun Bokde Uli Bromberg Christian Buechel Patricia Conrod Sylvane Desrivières Herta Flor Vincent Frouin Hugh Garavan Penny Gowland Andreas Heinz Bernd Ittermann Herve Lemaitre JeanLuc Martinot Eva Mennigen Frauke Nees MarieLaure Paillère Martinot Dimitri Papadopoulos Tomáš Paus Luise Poustka Sarah Jurk Michael N Smolka Nora C Vetter Henrik Walter Robert Whelan Gunter Schumann Juergen Gallinat and the IMAGEN consortium

Publish Date: 2016/06/25

Volume: 24, Issue: 6, Pages: 489-495

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Abstract

The test data were derived from the baseline assessment and first followup of the IMAGEN study a European multicenter and multidisciplinary research project on adolescent mental health In the present study 1004 participants were tested The characterization of personality was conducted with the NEOFFI at the age of 14 T1 The data on substance use were collected with the European School Survey Project on Alcohol and Other Drugs ESPAD questionnaire at the age of 16 T2 For the statistical analysis ttests and univariate analyses of variance were performedThe scores of Conscientiousness at T1 were significantly lower for adolescents with tobacco alcohol and cannabis experiences at T2 We found lower scores of Agreeableness at T1 in participants with tobacco and cannabis use at T2 Extraversion at T1 was significantly higher for adolescents with smoking experiences at T2 No significant associations between Neuroticism or Openness and future substance use were observedLow scores of Conscientiousness and Agreeableness seem to have the greatest value for a prediction of later experiences with substance use As the present study is the first one to examine the predictive value of the NEOFFI for future substance use in an adolescent sample further studies are necessary to enable a better applicability in a clinical contextThis work received support from the following sources the European Unionfunded FP6 Integrated Project IMAGEN Reinforcementrelated behaviour in normal brain function and psychopathology LSHMCT 2007–037286 the FP7 projects IMAGEMEND 602450 IMAgingGEnetics for MENtal Disorders and MATRICS 603016 the Innovative Medicine Initiative Project EUAIMS 115300–2 a Medical Research Council Programme Grant “Developmental pathways into adolescent substance abuse” 93558 the Swedish funding agency FORMAS the Medical Research Council and the Wellcome Trust Behavioural and Clinical Neuroscience Institute University of Cambridge the National Institute for Health Research NIHR Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King’s College London the Bundesministerium für Bildung und Forschung BMBF grants 01GS08152 01EV0711 eMED SysAlc01ZX1311AForschungsnetz AERIAL the Deutsche Forschungsgemeinschaft DFG grants SM 80/71 SM 80/72 SFB 940/1 and the National Institutes of Health USA Axon Testosterone and Mental Health during Adolescence RO1 MH08577201A1

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