Allergen specific sublingual immunotherapy in chil

Authors: Ivana ĐurićFilipović Marco Caminati Gordana Kostić Đorđe Filipović Zorica Živković

Publish Date: 2016/06/29

Volume: 12, Issue: 3, Pages: 283-290

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Abstract

The incidence of asthma and allergic rhinitis AR is significantly increased especially in younger children Current treatment for children with asthma and allergic rhinitis include allergen avoidance standard pharmacotherapy and immunotherapy Since standard pharmacotherapy is prescribed for symptoms immunotherapy at present plays an important role in the treatment of allergic diseases This article presents insights into the uptodate understanding of immunotherapy in the treatment of children with allergic rhinitis and asthmaNumerous studies have shown that sublingual application of allergen specific immunotherapy SLIT is an adequate safe and efficient substitution to subcutaneous route of allergens administration SCIT in the treatment of IgEmediated respiratory tract allergies in children According to the literature better clinical efficacy is connected with the duration of treatment and mono sensitized patientsAt least 3 years of treatment and stable asthma before the immunotherapy are positive predictors of good clinical efficacy and tolerability of SLIT SLIT reduces the symptoms of allergic diseases and the use of medicaments and improves the quality of life of children with the diseases

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