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Title of Journal: Arch Dermatol

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Abbravation: Archives of Dermatology

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American Medical Association

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DOI

10.1016/0009-2614(70)80184-1

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0003-987X

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Effects of Topical Fluorouracil on Normal Skin

Authors: Alvin S Zelickson Jess Mottaz Larry W Weiss
Publish Date: 1975/10/01
Volume: 111, Issue: 10, Pages: 1301-1306
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Abstract

• Daily application of 1 fluorouracil cream to normal white skin results in definite morphologic alterations of the epidermis Although clinical changes were not present electron microscopic examination of the tissue demonstrates changes especially pronounced in the epidermal keratinocytes These changes consist of cytoplasmic vacuoles alterations in the mitochondria Golgi complex and endoplasmic reticulum as well as widened extracellular spaces

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References

citation title=Fluorouracil Mechanism of action in human skin and actinic keratoses I Effect on DNA synthesis in vivo citation author=Eaglstein WH Weinstein GD Frost PArch Dermatol citation year=1970 citation volume=101 citation pages=132139

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  1. ONYCHOMYCOSIS UNIVERSALIS TRICHOPHYTINA ET EPIDERMOPHYTA: REPORT OF THE SEVENTH CASE THUS FAR RECORDED IN ENGLISH
  2. Basal Cell Epithelioma of the Sole
  3. Krinkle Finger Syndrome
  4. PHILADELPHIA PEDIATRIC SOCIETY AND PHILADELPHIA DERMATOLOGICAL SOCIETY
  5. n-Alkanes in the Skin-Reply
  6. Paul Ehrlich and His Impact on Dermatosyphilology
  7. Male-Type Alopecia, Alopecia Areata, and Normal Hair in Women: Family Histories
  8. Prevalence of the Metabolic Syndrome in Psoriasis: Results From the National Health and Nutrition Examination Survey, 2003-2006
  9. Comparative Percutaneous Absorption of Lindane and Permethrin
  10. SAN FRANCISCO DERMATOLOGICAL SOCIETY
  11. NEW YORK DERMATOLOGICAL SOCIETY
  12. CORRECTIVE SURGICAL PLANING OF SKIN: New Technique for Treatment of Acne Scars and Other Skin Defects
  13. SUGGESTED NOMENCLATURE FOR ULTRAVIOLET ZONES
  14. Multiple Minute Digitate Hyperkeratoses or Disseminated Spiked Hyperkeratosis
  15. Malignant Melanoma and Other Second Cutaneous Malignancies in Cutaneous T-Cell Lymphoma: The Influence of Additional Therapy After Total Skin Electron Beam Radiation
  16. Variation in Disease Expression?
  17. Comparison of Erbium:YAG and Carbon Dioxide Lasers in Resurfacing of Facial Rhytides
  18. Kaposi's Varicelliform Eruption With Ocular Involvement
  19. NEW ENGLAND DERMATOLOGICAL SOCIETY
  20. Update: AIDS Among Women—United States, 1994
  21. Cutaneous Alternariosis
  22. Cosmeceuticals: A Proposal for Rational Definition, Evaluation, and Regulation
  23. CHROMOBLASTOMYCOSIS: Report of Nine Cases from a Single Area in Louisiana
  24. PHYTOPHARMACOLOGIC TEST IN DERMATOLOGY: FURTHER STUDIES AND SOME CRITICAL ESTIMATIONS
  25. The Human Papillomaviruses: A Review
  26. A STUDY ON ULCUS PHAGEDENICUM CUTIS
  27. PHILADELPHIA DERMATOLOGICAL SOCIETY
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