Prevalence of the Metabolic Syndrome in Psoriasis

Authors: Thorvardur Jon Love Abrar A Qureshi Elizabeth Wood Karlson Joel M Gelfand Hyon K Choi

Publish Date: 2011/04/01

Volume: 147, Issue: 4, Pages: 419-424

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Abstract

Frequency distribution of the metabolic syndrome components according to the presence of psoriasis The dashed vertical line marks the cutoff for the definition of the metabolic syndrome with the columns to the right of this line representing those patients meeting the modified National Cholesterol Education Program Adult Treatment Panel III criteria The solid line represents the normal density plot showing a shift toward the right among patients with psoriasisLove TJ Qureshi AA Karlson EW Gelfand JM Choi HK Prevalence of the Metabolic Syndrome in Psoriasis Results From the National Health and Nutrition Examination Survey 20032006 Arch Dermatol 20111474419–424 doi101001/archdermatol2010370Main Outcome Measures  Prevalence of the metabolic syndrome defined by the revised National Cholesterol Education Program Adult Treatment Panel III definition and odds ratios for associations after adjustment for age sex race/ethnicity smoking status and Creactive protein levelsResults  The prevalence of the metabolic syndrome was 40 among psoriasis cases and 23 among controls According to 2008 US census data the projected number of patients with psoriasis aged 20 to 59 years with the metabolic syndrome was 27 million The univariate and multivariate odds ratios for patients with psoriasis and the metabolic syndrome were 216 95 confidence interval 116 to 403 and 196 101 to 377 respectively The most common feature of the metabolic syndrome among patients with psoriasis was abdominal obesity followed by hypertriglyceridemia and low levels of highdensity lipoprotein cholesterol

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