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Title of Journal: Exp Brain Res

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Abbravation: Experimental Brain Research

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Springer-Verlag

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DOI

10.1007/s100500050168

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1432-1106

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Information processing in long delay memoryguided

Authors: Thomas Nyffeler Charles PierrotDeseilligny Tobias Pflugshaupt Roman von Wartburg Christian W Hess René M Müri
Publish Date: 2003/10/25
Volume: 154, Issue: 1, Pages: 109-112
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Abstract

The performance of memoryguided saccades with two different delays 3 s and 30 s of memorisation was studied in eight subjects Single pulse transcranial magnetic stimulation TMS was applied simultaneously over the left and right dorsolateral prefrontal cortex DLPFC 1 s after target presentation In both delays stimulation significantly increased the percentage of error in amplitude of memoryguided saccades Furthermore the interfering effect of TMS was significantly higher in the short delay compared to that of the long delay paradigm The results are discussed in the context of a mixed model of spatial working memory control including two components First serial information processing with a predominant role of the DLPFC during the early period of memorisation and second parallel information processing which is independent from the DLPFC operating during longer delays

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