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Title of Journal: AIDS Behav

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Abbravation: AIDS and Behavior

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Springer US

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1573-3254

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Neurocognitive Aspects of Medication Adherence in

Authors: Drenna WaldropValverde Raymond L Ownby Frances L Wilkie Alison Mack Mahendra Kumar Lisa Metsch
Publish Date: 2006/02/17
Volume: 10, Issue: 3, Pages: 287-297
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Abstract

Cognitive deficits are associated with nonadherence to HIV medications HIVpositive injecting drug users IDUs are at particular risk for nonadherence and cognitive barriers to adherence specific to this population should therefore be identified The present study assessed the relation of three domains of cognitive functioning executive functions memory and psychomotor speed to selfreported antiretroviral adherence in a sample of HIVpositive IDUs Depression use of alcohol heroin cocaine/crack or marijuana in the last week were also included in the models Logistic regression analyses showed that only psychomotor slowing was significantly associated with nonadherence Executive functions memory depression and active alcohol and substance use were unrelated to adherence No other studies to date have exclusively linked psychomotor slowing to nonadherence in HIV infection Psychomotor slowing among our study sample was severe and suggests that when evident such slowing may be a valuable determinant for antiretroviral adherence among IDUsThis research was supported by a Development Award from the Drug Abuse and AIDS Research Center DAARC at the University of MiamiSchool of Medicine Department of Epidemiology funded by NIDA P30 DA 13870 This study was also supported in part by research grants DA 12792 and DA 13550

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  2. Adolescents’ Emotions Prior to Sexual Activity and Associations with Sexual Risk Factors
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  7. HIV Symptoms and Health-Related Quality of Life Prior to Initiation of HAART in a Sample of HIV-Positive South Africans
  8. The Impact of DSM-IV Mental Disorders on Adherence to Combination Antiretroviral Therapy Among Adult Persons Living with HIV/AIDS: A Systematic Review
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  11. Caregiver Role Overload and Network Support in a Sample of Predominantly Low-Income, African-American Caregivers of Persons Living with HIV/AIDS: A Structural Equation Modeling Analysis
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