Authors: Odile JeanniardMalet Gwenaëlle Gravis Fabrice Caillol Christian Pesenti Erwan Bories Marc Giovannini
Publish Date: 2010/07/17
Volume: 43, Issue: 1, Pages: 128-130
Abstract
We report the case of three severe esophagitis stage 4 responsible for digestive bleeding Two patients were taking anticoagulant that could worsen the bleeding but none were taking either antiplatelet or nonsteroidal antiinflammatory or corticosteroid that could favour erosion or ulceration of the digestive mucosa It seems that SUTENT® is responsible for the digestive bleedingCases of esophagitis induced by SUTENT® have already been reported but are rare and of mild severity Our three cases of esophagitis are severe with SUTENT® treatment as only risk factor and worsened by anticoagulant treatment for two patients It might be of interest preventively to treat these patients with inhibitors of proton pump
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