Authors: Alavieh Fateh Mohammad Ali Hosseinpour Feizi Reza Safaralizadeh Shirin Azarbarzin Reyhaneh Ravanbakhsh
Publish Date: 2016/06/02
Volume: 47, Issue: 4, Pages: 399-403
Abstract
No significant relationship was found between miR1287 expression levels and clinicopathological features Showing significant changes overall MiR1287 was significantly upregulated in the group of CRC samples compared with matched noncancerous tissue samples A receiver operating characteristic ROC curve also showed ROC area AROC of 34 with 10 and 002 sensitivity and specificity respectively Expression of miR1287 with a value of 034 P value = 198 and P 005 revealed that this microRNA has a low sensitivity and specificity to be regarded as a tumor markerAll study participants were born in East Azerbaijan Iran and none of them had taken chemotherapy or radiotherapy and adjuvant therapy The study was accepted by the Research Ethics Committee of Imam Reza Hospital in conformity with institutional protocol and informed consents were obtained from all patients
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