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Title of Journal: Virol Sin

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Abbravation: Virologica Sinica

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SP Wuhan Institute of Virology, CAS

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10.1007/bf00746860

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1995-820X

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Hepatitis C virus experimental model systems and a

Authors: Susan L Uprichard
Publish Date: 2010/07/28
Volume: 25, Issue: 4, Pages: 227-245
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Abstract

An estimated 130 million people worldwide are chronically infected with hepatitis C virus HCV making it a leading cause of liver disease worldwide Because the currently available therapy of pegylated interferonalpha and ribavirin is only effective in a subset of patients the development of new HCV antivirals is a healthcare imperative This review discusses the experimental models available for HCV antiviral drug research recent advances in HCV antiviral drug development as well as active research being pursued to facilitate development of new HCVspecific therapeutics


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