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Title of Journal: Biometals

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Abbravation: BioMetals

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Springer Netherlands

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DOI

10.1016/0304-4157(95)00006-d

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1572-8773

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Arsenic trioxide versus tetraarsenic oxide in biom

Authors: Zdenka Šlejkovec Ingrid Falnoga Johannes T van Elteren
Publish Date: 2011/08/28
Volume: 25, Issue: 1, Pages: 231-235
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Abstract

This work presents an analytical chemist’s view on the sometimes unconscious use of arsenic trioxide in biomedical research Arsenic trioxide is a frequently used chemical in cancer treatment research and its action to various malignant cells has been extensively studied and published Unfortunately some research articles show trivial errors with regards to background knowledge of the chemical handling the chemical experimental design and interpretation of results like eg in a range of articles comparing advantages of tetraarsenic oxide over arsenic trioxide dimeric/monomeric although the dissolution of both yields the same active compound HAsO2 To fully understand the implications of these errors we will highlight some of them with the intent to harmonize future work in this field

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