Authors: Panagiotis Steliopoulos
Publish Date: 2012/08/17
Volume: 17, Issue: 5, Pages: 543-547
Abstract
Generally the cutoff point of a screening assay is defined through a onesided prediction limit obtained from a given sample of blanks Depending on the assumptions one is willing to make about the underlying data distribution different types of prediction limits can be employed In this paper Monte Carlo simulations are used to illustrate the coverage performance of normal lognormal and nonparametric prediction limits under normal and nonnormal conditions
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