Authors: Samuele Baldasseroni Enrico Mossello Benedetta Romboli Francesco Orso Claudia Colombi Stefano Fumagalli Andrea Ungar Francesca Tarantini Giulio Masotti Niccolò Marchionni
Publish Date: 2013/07/26
Volume: 22, Issue: 4, Pages: 308-313
Abstract
Background and aims Cognitive decline and heart failure frequently coexist in the elderly Although an epidemiologic association may partially explain this finding cerebral hypoperfusion and cardioembolism have been advocated as pathophysiological links The aim of the present study was to evaluate the relationship between mild cognitive decline and exercise capacity in older outpatients with chronic heart failure CHF Methods We studied 80 elderly outpatients with stable CHF mainly of ischemic etiology assessing total exercise capacity with the 6minute walking test 6MWT and global cognitive function with the Mini Mental State Examination MMSE CHF severity emotional status comorbidity disability and diseasespecific quality of life were also determined at the time of enrolment Results A positive association was observed between the distance walked at 6MWT and MMSE score even after adjusting for demographic parameters indexes of CHF severity comorbidities level of disability and quality of life Conclusions An easy and reliable measure of cardiovascular global performance is independently associated with cognitive function in older outpatients affected by CHF In the context of global aging this observation emphasizes the importance of a comprehensive assessment encompassing a standard brief and reliable cognitive evaluation in elderly CHF outpatients
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