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Title of Journal: Aging Clin Exp Res

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Abbravation: Aging Clinical and Experimental Research

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Springer International Publishing

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DOI

10.1002/neu.480220703

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ISSN

1720-8319

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Sarcopenia and sarcopenic obesity in comparison p

Authors: Simone Perna Gabriella Peroni Milena Anna Faliva Arianna Bartolo Maurizio Naso Alessandra Miccono Mariangela Rondanelli
Publish Date: 2017/02/23
Volume: 29, Issue: 6, Pages: 1249-1258
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Abstract

A standardized comprehensive geriatric assessment was performed We enrolled 639 elderly subjects 196 men 443 women with a mean age of 8090 ± 777 years Analysis of variance and a multinomial logistic regression analysis adjusting for covariates were used to assess the differences between groupsThe prevalence of S was 1242 in women and 2347 in men SO was 813 in women and 2245 in men Data showed that either groups had a functional impairment Barthel index  50 points S had the mean value of erythrocyte sedimentation rate ESR 15 mm/h CPR 050 mg/dl homocysteine 12 micromol/l and hemoglobin 12 g/dl Ferritin level over the range 145 mcg/dl was detected in either cohort due to inflammation SO had glycemia 110 mg/dl Key differences in S cohort versus healthy were a reduction in functional impairment p  0001 an increase in white blood cell p  001 a decrease in iron level p  005 in electrolytes balance Na p  001 and Cl p  001 and tyroid function TSH p  0001 In addition S had higher state of inflammation erythrocyte sedimentation rate p  005 and Creactive protein p  001 and an increase of risk of fractures FRAX OR 107 p  0001 risk of malnutrition mini nutritional assessment p  0001 and risk of edema extra cellular water p  0001 In SO cohort an increase in white blood cell p  0001 and erythrocyte sedimentation rate p  005 was observed


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