Authors: Simone Perna Gabriella Peroni Milena Anna Faliva Arianna Bartolo Maurizio Naso Alessandra Miccono Mariangela Rondanelli
Publish Date: 2017/02/23
Volume: 29, Issue: 6, Pages: 1249-1258
Abstract
A standardized comprehensive geriatric assessment was performed We enrolled 639 elderly subjects 196 men 443 women with a mean age of 8090 ± 777 years Analysis of variance and a multinomial logistic regression analysis adjusting for covariates were used to assess the differences between groupsThe prevalence of S was 1242 in women and 2347 in men SO was 813 in women and 2245 in men Data showed that either groups had a functional impairment Barthel index 50 points S had the mean value of erythrocyte sedimentation rate ESR 15 mm/h CPR 050 mg/dl homocysteine 12 micromol/l and hemoglobin 12 g/dl Ferritin level over the range 145 mcg/dl was detected in either cohort due to inflammation SO had glycemia 110 mg/dl Key differences in S cohort versus healthy were a reduction in functional impairment p 0001 an increase in white blood cell p 001 a decrease in iron level p 005 in electrolytes balance Na p 001 and Cl p 001 and tyroid function TSH p 0001 In addition S had higher state of inflammation erythrocyte sedimentation rate p 005 and Creactive protein p 001 and an increase of risk of fractures FRAX OR 107 p 0001 risk of malnutrition mini nutritional assessment p 0001 and risk of edema extra cellular water p 0001 In SO cohort an increase in white blood cell p 0001 and erythrocyte sedimentation rate p 005 was observed
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