Depressive symptomatology and cortisol concentrati

Authors: Mayle Andrade Moreira Ricardo Oliveira Guerra Aline do Nascimento Falcão Freire Cristiano dos Santos Gomes Álvaro Campos Cavalcanti Maciel

Publish Date: 2015/05/19

Volume: 28, Issue: 1, Pages: 131-137

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Abstract

Crosssectional study is composed of 256 elderly ≥65 years Depressive symptomatology was evaluated by the Center for Epidemiologic StudiesDepression Scale and cortisol concentrations by salivary collection upon waking 30 and 60 min after waking at 3 pm and before bed in addition to composite measurements Sociodemographic and health conditions were evaluated For analysis of the cortisol measurements in relation to depressive symptomatology and between genders the Student’s t test was used For cortisol measurements in every curve analysis of variance for repeated measurements with Bonferroni post hoc test was usedThere were significant salivary cortisol differences upon awakening among elderly with and without depressive symptomatology p = 004 There was no significance in relation to gender Between measurements of each curve elderly with depressive symptomatology showed no significant difference between the 1st measure in relation to the 2nd and 3rd and also between the 4th and 5th demonstrating higher cortisol night levels in elderly with depressive symptomatology without decline with curve plane aspectThe relationship between depressive symptomatology and hypocortisolism throughout the day seems to exist However in Brazil adverse life conditions can lead to chronic stress and be sufficient factors to superpose biggest differences that could exist in relation to the presence of depressive symptomatologyWe thank all the participants of this research and the physiotherapists who worked as interviewers during data collection This work has been funded by the National Council for Scientific and Technological Development Conselho Nacional de Desenvolvimento Científico e Tecnológico—CNPq as project 474728/20099All procedures performed in studies involving human participants were in accordance with the Research Ethics Committee of the Universidade Federal do Rio Grande do Norte as part of a larger study called “Functional performance load allostatic and biomarkers stress in the elderly residents in the community” CEP/HUOL 481/10 in accordance with resolution 466/12 National Health Council and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards

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