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Title of Journal: Aging Clin Exp Res

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Abbravation: Aging Clinical and Experimental Research

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Springer International Publishing

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DOI

10.1007/s11104-011-0980-y

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1720-8319

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Changes in body composition and use of blood chole

Authors: A Arnarson A Ramel O G Geirsdottir P V Jonsson I Thorsdottir
Publish Date: 2013/12/01
Volume: 26, Issue: 3, Pages: 287-292
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Abstract

Aging is associated with an impairment of blood lipids The present study investigated the response of blood lipids to resistance exercise in old adults The particular aim was to investigate whether the response of blood lipids is associated with changes in body composition of blood lipid medicationSubjects N = 236 737 ± 57 years 582  female participated in a 12week resistance exercise program 3 times/week 3 sets 6–8 repetitions at 75–80  of the 1repetition maximum designed to increase strength and muscle mass of major muscle groups Body composition drug use triglycerides TG total cholesterol TC lowdensity lipoprotein LDL and highdensity lipoprotein HDL were assessed at baseline and endpointThe concentrations of HDL −6 mg/dl LDL −18 mg/dl TC −26 mg/dl and TG −12 mg/g decreased significantly during the study period A reduction in fat mass by 1 kg predicted a reduction in TG 50 mg/dl P = 0017 and a gain in lean body mass by 1 kg predicted also a reduction in TG −45 mg/dl P = 0023 The use of blood cholesterol lowering drugs predicted greater reductions in TC −169 mg/dl P = 0032 and LDL −118 mg/dl P = 0038 during trainingTG TC LDL and HDL decreased significantly after 12 weeks of progressive resistance exercise in old adults Changes in body composition ie reduction in fat mass and gain in lean body mass improved the blood lipid profile Use of blood lipid lowering drugs was associated with greater reductions in TC and LDL after the trainingThis study was part of the IceProQualita project which was funded by the Icelandic Technology Development Fund No 071323008 Research Fund of the University of Iceland a grant from Landspitali University Hospital Research Fund and the Helga Jonsdottir and Sigurlidi Kristjansson Geriatric Research Fund The trial is registered at the US National Library of Medicine Nr NCT01074879


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