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Title of Journal: J Nucl Cardiol

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Abbravation: Journal of Nuclear Cardiology

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Springer US

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DOI

10.1002/jhet.5570400203

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1532-6551

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Lessons learned from MPI and physiologic testing i

Authors: Lawrence M Phillips Rory Hachamovitch Daniel S Berman Ami E Iskandrian James K Min Michael H Picard Raymond Y Kwong Matthias G Friedrich Marielle ScherrerCrosbie Sean W Hayes Tali Sharir Gilbert Gosselin Marco Mazzanti Roxy Senior Rob Beanlands Paola Smanio Abhi Goyal Mouaz AlMallah Harmony Reynolds Gregg W Stone David J Maron Leslee J Shaw
Publish Date: 2013/08/21
Volume: 20, Issue: 6, Pages: 969-975
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Abstract

There is a preponderance of evidence that in the setting of an acute coronary syndrome an invasive approach using coronary revascularization has a morbidity and mortality benefit However recent stable ischemic heart disease SIHD randomized clinical trials testing whether the addition of coronary revascularization to guidelinedirected medical therapy GDMT reduces death or major cardiovascular events have been negative Based on the evidence from these trials the primary role of GDMT as a front line medical management approach has been clearly defined in the recent SIHD clinical practice guideline the role of prompt revascularization is less precisely defined Based on data from observational studies it has been hypothesized that there is a level of ischemia above which a revascularization strategy might result in benefit regarding cardiovascular events However eligibility for recent negative trials in SIHD has mandated at most minimal standards for ischemia An ongoing randomized trial evaluating the effectiveness of randomization of patients to coronary angiography and revascularization as compared to no coronary angiography and GDMT in patients with moderatesevere ischemia will formally test this hypothesis The current review will highlight the available evidence including a review of the published and ongoing SIHD trials


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  2. Anatomy and physiology of coronary blood flow
  3. Fifty years of progress in radionuclide assessment of myocardial perfusion
  4. Buccal caffeine for the routine reversal of Persantine
  5. Multimodality molecular imaging in predicting ventricular arrhythmias and sudden cardiac death
  6. Mentorship at Distance: A new initiative of the Journal of Nuclear Cardiology
  7. Safety of vasodilator stress myocardial perfusion imaging in patients with elevated cardiac biomarkers
  8. ASNC Model Coverage Policy: Single photon myocardial perfusion imaging
  9. A selection of recent, original research papers
  10. Effect of Bayesian-penalized likelihood reconstruction on [13N]-NH3 rest perfusion quantification
  11. Impaired cardiac PET image quality due to delayed 82 Rubidium dose delivery to the heart
  12. Complete somatostatin-induced insulin suppression combined with heparin loading does not significantly suppress myocardial 18F-FDG uptake in patients with suspected cardiac sarcoidosis
  13. Left ventricular mechanical dyssynchrony by phase analysis as a prognostic indicator in heart failure
  14. “Same-Patient Processing” for multiple cardiac SPECT studies. 1. Improving LV segmentation accuracy
  15. Optimizing quantitative myocardial perfusion by positron emission tomography for guiding CAD management
  16. Effect of aminophylline administration on the diagnostic yield of vasodilator myocardial perfusion imaging
  17. Quantitative I-123 mIBG SPECT in differentiating abnormal and normal mIBG myocardial uptake
  18. Warranty period of normal stress myocardial perfusion imaging in diabetic patients: A propensity score analysis
  19. Coronary steal: Revealing the diagnosis with quantitative cardiac PET/CT
  20. Life-Threatening Ventricular Arrhythmias: Current Role of Imaging in Diagnosis and Risk Assessment
  21. Quantifying predictive accuracy in survival models
  22. Regadenoson pharmacologic rubidium-82 PET: A comparison of quantitative perfusion and function to dipyridamole
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  24. Prognostic value of myocardial metabolic imaging with BMIPP in the spectrum of coronary artery disease: A systematic review
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  26. What have we learned from CONFIRM? Prognostic implications from a prospective multicenter international observational cohort study of consecutive patients undergoing coronary computed tomographic angiography
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  28. Multicenter investigation comparing a highly efficient half-time stress-only attenuation correction approach against standard rest-stress Tc-99m SPECT imaging
  29. ASNC Announcement
  30. The additive prognostic value of perfusion and functional data assessed by quantitative gated SPECT in women
  31. New software methods to cope with reduced counting statistics: shorter SPECT acquisitions and many more possibilities
  32. Impact of time-of-flight on qualitative and quantitative analyses of myocardial perfusion PET studies using 13 N-ammonia
  33. Impact of time-of-flight on qualitative and quantitative analyses of myocardial perfusion PET studies using 13 N-ammonia
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