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Title of Journal: J Nucl Cardiol

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Abbravation: Journal of Nuclear Cardiology

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Springer US

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DOI

10.1002/asi.1118

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1532-6551

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LifeThreatening Ventricular Arrhythmias Current

Authors: Saurabh Malhotra John M Canty
Publish Date: 2016/01/15
Volume: 23, Issue: 6, Pages: 1322-1334
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Abstract

Sudden cardiac arrest continues to be a major cause of death from cardiovascular disease but our ability to predict patients at the highest risk of developing lethal ventricular arrhythmias remains limited Left ventricular ejection fraction is inversely related to the risk of sudden death but has a low sensitivity and specificity for the population at risk Nevertheless it continues to be the main variable considered in identifying patients most likely to benefit from implantable defibrillators to prevent sudden death Imaging myocardial sympathetic innervation with PET and SPECT as well as imaging characteristics of myocardial infarcts using gadoliniumenhanced cardiac magnetic resonance are emerging as imaging modalities that may further refine patient selection beyond ejection fraction This review will primarily focus on employing advanced imaging approaches to identify patients with left ventricular dysfunction that are most likely to develop lethal arrhythmias and benefit from inserting a primary prevention implantable cardiac defibrillator While not yet tested in prospective studies we will review risk prediction models incorporating quantitative imaging and biomarkers that have been developed that appear promising to identify those at highest risk of sudden death


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Other Papers In This Journal:

  1. Anatomy and physiology of coronary blood flow
  2. Anatomy and physiology of coronary blood flow
  3. Fifty years of progress in radionuclide assessment of myocardial perfusion
  4. Buccal caffeine for the routine reversal of Persantine
  5. Multimodality molecular imaging in predicting ventricular arrhythmias and sudden cardiac death
  6. Mentorship at Distance: A new initiative of the Journal of Nuclear Cardiology
  7. Safety of vasodilator stress myocardial perfusion imaging in patients with elevated cardiac biomarkers
  8. ASNC Model Coverage Policy: Single photon myocardial perfusion imaging
  9. A selection of recent, original research papers
  10. Effect of Bayesian-penalized likelihood reconstruction on [13N]-NH3 rest perfusion quantification
  11. Impaired cardiac PET image quality due to delayed 82 Rubidium dose delivery to the heart
  12. Complete somatostatin-induced insulin suppression combined with heparin loading does not significantly suppress myocardial 18F-FDG uptake in patients with suspected cardiac sarcoidosis
  13. Left ventricular mechanical dyssynchrony by phase analysis as a prognostic indicator in heart failure
  14. “Same-Patient Processing” for multiple cardiac SPECT studies. 1. Improving LV segmentation accuracy
  15. Optimizing quantitative myocardial perfusion by positron emission tomography for guiding CAD management
  16. Lessons learned from MPI and physiologic testing in randomized trials of stable ischemic heart disease: COURAGE, BARI 2D, FAME, and ISCHEMIA
  17. Effect of aminophylline administration on the diagnostic yield of vasodilator myocardial perfusion imaging
  18. Quantitative I-123 mIBG SPECT in differentiating abnormal and normal mIBG myocardial uptake
  19. Warranty period of normal stress myocardial perfusion imaging in diabetic patients: A propensity score analysis
  20. Coronary steal: Revealing the diagnosis with quantitative cardiac PET/CT
  21. Quantifying predictive accuracy in survival models
  22. Regadenoson pharmacologic rubidium-82 PET: A comparison of quantitative perfusion and function to dipyridamole
  23. Incremental diagnostic benefit of resolution recovery software in patients with equivocal myocardial perfusion single-photon emission computed tomography (SPECT)
  24. Prognostic value of myocardial metabolic imaging with BMIPP in the spectrum of coronary artery disease: A systematic review
  25. What are the necessary corrections for dynamic cardiac SPECT?
  26. What have we learned from CONFIRM? Prognostic implications from a prospective multicenter international observational cohort study of consecutive patients undergoing coronary computed tomographic angiography
  27. Advances in myocardial perfusion imaging
  28. Multicenter investigation comparing a highly efficient half-time stress-only attenuation correction approach against standard rest-stress Tc-99m SPECT imaging
  29. ASNC Announcement
  30. The additive prognostic value of perfusion and functional data assessed by quantitative gated SPECT in women
  31. New software methods to cope with reduced counting statistics: shorter SPECT acquisitions and many more possibilities
  32. Impact of time-of-flight on qualitative and quantitative analyses of myocardial perfusion PET studies using 13 N-ammonia
  33. Impact of time-of-flight on qualitative and quantitative analyses of myocardial perfusion PET studies using 13 N-ammonia
  34. Dual molecular imaging for targeting metalloproteinase activity and apoptosis in atherosclerosis: molecular imaging facilitates understanding of pathogenesis
  35. Challenges of cardiac inflammation imaging with F-18 FDG positron emission tomography
  36. Acute hyperglycemia causes microvascular damage, leading to poor functional recovery and remodeling in patients with reperfused ST-segment elevation myocardial infarction

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