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Title of Journal: Cardiovasc Intervent Radiol

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Abbravation: CardioVascular and Interventional Radiology

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Springer US

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DOI

10.1007/s00018-005-5500-x

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1432-086X

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Change in Imaging Findings on AngiographyAssisted

Authors: Rika Yoshimatsu Takuji Yamagami Masaki Ishikawa Kenji Kajiwara Hiroshi Aikata Kazuaki Chayama Kazuo Awai
Publish Date: 2015/12/28
Volume: 39, Issue: 6, Pages: 865-874
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Abstract

To evaluate changes in imaging findings on CT during hepatic arteriography CTHA and CT during arterial portography CTAP by balloon occlusion of the treated artery and their relationship with iodized oil accumulation in the tumor during balloonoccluded transcatheter arterial chemoembolization BTACEBoth BTACE and angiographyassisted CT were performed for 27 hepatocellular carcinomas Tumor enhancement on selective CTHA with/without balloon occlusion and iodized oil accumulation after BTACE were evaluated Tumorous portal perfusion defect size on CTAP was compared with/without balloon occlusion Factors influencing discrepancies between selective CTHA with/without balloon occlusion and the degree of iodized oil accumulation were investigatedAmong 27 tumors tumor enhancement on selective CTHA changed after balloon occlusion in 14 decreased 11 increased 3 In 18 tumors there was a discrepancy between tumor enhancement on selective CTHA with balloon occlusion and the degree of accumulated iodized oil which was higher than the tumor enhancement grade in all 18 The tumorous portal perfusion defect on CTAP significantly decreased after balloon occlusion in 18 of 20 tumors mean decrease from 219 to 191 mm in diameter p = 00001 No significant factors influenced discrepancies between selective CTHA with/without balloon occlusion Central area tumor location poor tumor enhancement on selective CTHA with balloon occlusion and no decrease in the tumorous portal perfusion defect area on CTAP after balloon occlusion significantly influenced poor iodized oil accumulation in the tumorDr Chayama receives honoraria more than 1000000 yen or research funding more than 2000000 yen from MSD Co Ltd Tanabe Co Ltd Roche Co Ltd Toray Co Ltd Chugai Co Ltd Sumitomo Co Ltd Otuka Co Ltd and DaiichiSankyo Co Ltd Dr Awai receives research funding more than 2000000 yen from Toshiba Medical Systems Co Ltd The other authors have no conflicts of interestAll procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards

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