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Title of Journal: Pituitary

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Abbravation: Pituitary

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Springer US

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DOI

10.1007/978-3-642-35795-4_30

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1573-7403

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Low frequency of cardniac arrhythmias and lack of

Authors: Leila Warszawski Leandro Kasuki Rodrigo Sá Cintia Marques dos Santos Silva Isabela Volschan Ilan Gottlieb Roberto Coury Pedrosa Mônica R Gadelha
Publish Date: 2016/09/03
Volume: 19, Issue: 6, Pages: 582-589
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Abstract

The incidence of arrhythmias may be increased in acromegaly but the pathophysiologic mechanisms involved are still unclear and it has never been correlated with structural heart changes analyzed by the goldstandard method cardiac magnetic resonance CMRThirtysix patients were studied at baseline and 28 were reevaluated after 1 year of SA treatment There were 13 females and median age was 48 years 20–73 years Nine patients 32  were controlled after treatment No sustained arrhythmias were reported in the 24h Holter No arrhythmiarelated symptoms were observed Only two patients presented left ventricular hypertrophy and three patients presented fibrosis at baseline There was no correlation of the left ventricular mass with the number of episodes of arrhythmias and they were not more prevalent in the patients presenting cardiac fibrosisWe found no sustained arrhythmias and a lack of arrhythmiarelated symptoms at baseline and after 1 year of SA treatment in a contemporary cohort of acromegaly patients that also present a low frequency of structural heart changes indicating that these patients may have a lower frequency of heart disease than previously reported

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  3. Somatostatin receptor ligands in the treatment of acromegaly
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  13. Two cases of Kallmann syndrome associated with empty sella
  14. Multiple head and neck tumors following treatment for craniopharyngioma
  15. Modulation of VEGF/Flk-1 receptor expression in the rat pituitary GH3 cell line by growth factors
  16. Acromegalic gigantism, physicians and body snatching. Past or present?
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  20. Differential diagnosis of ACTH-dependent hypercortisolism: imaging versus laboratory
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